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UTL-5g

SKU: orb1298588

Description

UTL-5g is a novel small molecule TNF-α inhibitor investigated as a chemoprotective and radioprotective agent. Research demonstrates its efficacy in mitigating cisplatin-induced nephrotoxicity, hepatotoxicity, and hematotoxicity in murine models by modulating serum biomarkers and inflammatory cytokines.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number646530-37-2
MW271.1
Purity99.83%
FormulaC11H8Cl2N2O2
SMILESCc1cc(no1)C(=O)Nc1ccc(Cl)cc1Cl
TargetTNF
Solubility10% DMSO+90% Corn Oil:2 mg/mL (7.38 mM);DMSO:27.5 mg/mL (101.44 mM)

Bioactivity

In Vivo
UTL-5g (GBL-5g) reduces elevated TGF-β and TNF-α levels resulting from lung irradiation.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, liver, Inhibitor, GBL-5g, hepatotoxicity, anti-inflammatory, 3-Isoxazolecarboxamide, N-(2,4-dichlorophenyl)-5-methyl-, acute, chemoprotective, Tumor Necrosis Factor Receptor, TNF Receptor, TNFR, TNF-α, toxicity, radioprotective, UTL 5g, UTL5g, UTL-5g

Similar Products

  • UTL-5g [orb1217769]

    >98% (HPLC)

    646530-37-2

    271.1

    C11H8Cl2N2O2

    1 g, 500 mg, 200 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg
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Key Properties

No computed properties available.

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UTL-5g (orb1298588)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

2 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 110.00
5 mg
$ 110.00
10 mg
$ 140.00
25 mg
$ 250.00
50 mg
$ 330.00
100 mg
$ 450.00
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