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VDX-111

SKU: orb2565078

Description

VDX-111, a vitamin D analog, induces necroptotic cell death in ovarian cancer cells via RIPK1/RIPK3 pathway activation and cytokine production. It has demonstrated cytotoxic effects in vitro and antitumor efficacy in mouse xenograft models, supporting its use in oncology research focused on programmed necrosis.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number158983-23-4
MW537.57
FormulaC29H45BrO4
SMILESC[C@@]12[C@](\C(=C\C=C/3\C[C@@H](OC(CBr)=O)C[C@H](O)C3=C)\CCC1)(CC[C@@]2([C@@H](CCCC(C)(C)O)C)[H])[H]
TargetRIP kinase,Necroptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

VDX-111 (orb2565078)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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