Vitamin E succinate

SKU: orb1944993

Description

Vitamin E succinate (D-alpha-Tocopherol Succinate) is a vitamin E derivative with demonstrated pro-apoptotic and antitumor properties in vitro and in vivo. It is investigated as a potential chemotherapeutic adjuvant and is also used in biochemical synthesis, such as for biocoupling compounds.

Research Area

Cell Biology

Images & Validation

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Key Properties

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CAS Number	4345-03-3
MW	530.78
Purity	99.24%
Formula	C₃₃H₅₄O₅
SMILES	CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(=O)CCC(O)=O)c(C)c(C)c2O1
Target	Apoptosis
Solubility	DMSO:120 mg/mL (226.08 mM)

Bioactivity

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In Vivo	In female C57BL/6 mice aged 6-8 weeks with TC-1 tumor cells,Vitamin E succinate (2 mg/kg; intraperitoneal injection; three times every 2 days, starting from the injection of TC-1 tumor cells and continuing for 10 to 14 days) decreased tumor volume. Read more...
In Vitro	In the HEI-OC1 cell line,Vitamin E succinate (1-20 μM; 24 hours) significantly induced cytotoxicity at a concentration of 20 μM and showed a higher cytotoxic potency compared to 10 μM. Read more...

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Apoptosis, D-α-Tocopherol Succinate

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Compound Identifiers

PubChem CID

20353 ↗

Key Properties

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No computed properties available.

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