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VLX 1500

SKU: orb3172813

Description

VLX 1500 is a potent deubiquitinating enzyme (DUBs) inhibitor designed to overcome resistance to traditional proteasome inhibitors. It triggers ER stress-mediated apoptosis by specifically blocking USP14/UCHL5 activity on the 19S regulatory particle, leading to a lethal accumulation of ubiquitinated proteins, widely used in drug target screening for relapsed hematological malignancies.

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Key Properties

CAS Number330450-45-8
MW419.39
FormulaC22H17N3O6
SMILESO=C(N1CC(C(C(C1)=CC2=CC=C([N+]([O-])=O)C=C2)=O)=CC3=CC=C([N+]([O-])=O)C=C3)C=C
TargetDUB

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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VLX 1500 (orb3172813)

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5 mg
$ 80.00
10 mg
$ 100.00
25 mg
$ 130.00
50 mg
$ 170.00
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