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Vomicine

SKU: orb1297603

Description

Vomicine is a natural alkaloid isolated from Strychnos nux-vomica. Extracts containing this compound have demonstrated antihyperglycemic effects in animal studies, suggesting its relevance for research in metabolic disorders and diabetes.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number125-15-5
MW380.44
Purity99.83%
FormulaC22H24N2O4
SMILES[H][C@@]12N3c4c(cccc4O)[C@@]11CCN(C)CC4=CCO[C@@]([H])(CC3=O)[C@]2([H])[C@@]4([H])CC1=O
TargetSTING,Others
SolubilityDMSO:50 mg/mL (131.43 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.63 mM)

Bioactivity

In Vitro
Reinvestigation of Strychnos icaja Baillon resulted in the isolation of Vomicine, isostrychnine and of three new sungucine derivatives, named isosungucine (8), 18-hydroxy-sungucine (9) and 18-hydroxy-isosungucine (10). They were identified by detailed spectroscopic methods. The complete 1H- and 13C-NMR study of sungucine was also realized. Some of these compounds were highly active against Plasmodium falciparum in vitro and more particularly against the chloroquine-resistant strain

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, antidiabetic, activity, alkaloid, Vomicine

Similar Products

  • Vomicine [orb1218991]

    >98% (HPLC)

    125-15-5

    380.44

    C22H24N2O4

    10 mg, 25 mg, 1 g, 500 mg, 200 mg, 50 mg, 100 mg, 5 mg
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Key Properties

No computed properties available.

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Vomicine (orb1297603)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

100 mg
1 mg
$ 90.00
5 mg
$ 160.00
1 ml x 10 mM (in DMSO)
$ 180.00
10 mg
$ 220.00
25 mg
$ 340.00
50 mg
$ 470.00