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Yakuchinone A

SKU: orb1217650

Description

Yakuchinone A is a natural product isolated from Alpinia oxyphylla Miquel. Yakuchinone-A has strong inhibitory effects on the synthesis of prostaglandins and leukotrienes in vitro. Yakuchinone A inhibits the expression of cyclooxygenase-2 and of inducible nitric oxide synthase (iNOS).

Images & Validation

Key Properties

CAS Number78954-23-1
MW312.41
Purity>98% (HPLC)
FormulaC20H24O3
SMILESO=C(CCCCC1=CC=CC=C1)CCC2=CC=C(O)C(OC)=C2
TargetOthers
SolubilityDMSO:10 mM

Bioactivity

In Vivo
Animal model: Female C57BL/6 mice. Dosage: 50 mg/kg. Administration: i.p. , daily, 14 days. Result: Showed a significant EAE score reduction from Day 9 to Day 15 after EAE onset.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Yakuchinone-A

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Yakuchinone A (orb1217650)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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Available Sizes

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200 mg
500 mg
5 mg
$ 220.00
10 mg
$ 350.00
25 mg
$ 670.00
50 mg
$ 950.00
100 mg
$ 1,290.00