YM-31636 free base

SKU: orb2802380

Description

YM-31636 (free base) is an orally active, potent, and selective agonist of the 5-HT3 receptor with a pKi value of 9.67. This compound induces contraction in isolated guinea pig distal colon and provokes tachycardia in isolated guinea pig right atrium, demonstrating a relative intrinsic activity of about 0.23. YM-31636 (free base) holds potential for research in constipation management.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	159081-22-8
MW	253.32
Formula	C₁₄H₁₁N₃S
SMILES	N1=CNC(=C1)CC2=NC=3C=4C=CC=CC4CC3S2
Target	5-HT Receptor

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

5-HT Receptor

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