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Z-L(D-Val)G-CHN2

SKU: orb2278859

Description

Z-L(D-Val)G-CHN2 is a cell-permeable, irreversible cysteine protease inhibitor. This tripeptidyl derivative mimics a host protease-binding region, selectively inhibiting herpes simplex virus and SARS-CoV-2 replication (EC50 = 190 nM against 3CLpro) in vitro, with minimal effect on poliovirus.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Images & Validation

Key Properties

MW445.51
FormulaC22H31N5O5
TargetHSV,SARS-CoV,Cysteine Protease

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

Z-L(D-Val)G-CHN2 (orb2278859)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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