Zaltoprofen sulfoxide

SKU: orb3174987

Description

Zaltoprofensulfoxide (Compound M2) is the primary metabolite of Zaltoprofen. It is a potent and selective COX-2 inhibitor (IC50 = 45.38 nM) and also acts as a PPAR-γ activator. Zaltoprofen sulfoxide effectively suppresses NF-κB and MAPK inflammatory signaling pathways, alleviating LPS-induced acute lung injury. This compound is valuable for studying acute lung injury.

Images & Validation

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Key Properties

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CAS Number	134085-79-3
MW	314.36
Formula	C₁₇H₁₄O₄S
SMILES	O=C(O)C(C1=CC=C2C(=C1)CC(=O)C=3C=CC=CC3S2=O)C
Target	NF-κB,PPAR,Drug Metabolite,p38 MAPK,COX

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

NF-κB,PPAR,Drug Metabolite,p38 MAPK,COX

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