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ZSTK3744 hydrochloride

SKU: orb3210639

Description

ZSTK3744 hydrochloride is an aryl hydrocarbon receptor (AhR) agonist. It can directly bind to AhR, leading to the upregulation of AhR target genes such as CYP1A1, CYP1B1, and TIPARP, thereby mediating cell growth inhibition in triple-negative breast cancer cells. ZSTK3744 hydrochloride induces apoptosis in these cells and exhibits antitumor activity, making it useful for research on chemotherapy-resistant triple-negative breast cancer.

Images & Validation

Key Properties

TargetCytochromes P450,Caspase,Aryl Hydrocarbon Receptor,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information