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2,3-Dihydroxy-4-methoxyacetophenone

SKU: orb1217711

Description

2,3-Dihydroxy-4-methoxyacetophenone is a natural product,it improves cognitive function and may be helpful for the treatment of Alzheimer's disease.

Images & Validation

Key Properties

CAS Number708-53-2
MW182.17
Purity>98% (HPLC)
FormulaC9H10O4
SMILESCC(C1=CC=C(OC)C(O)=C1O)=O
TargetCalcium Channel
SolubilityDMSO:10 mM

Bioactivity

In Vivo
2, 3-dihydroxy-4-methoxyacetophenone (50 mg/kg; po) improves the impairment of spatial memory induced by scopolamine.
In Vitro
2, 3-Dihydroxy-4-methoxyacetophenone protects HT22 cells on glutamate induced cell-death in a dose-dependent manner (EC50 = 10.94 μM). 2, 3-Dihydroxy-4-methoxyacetophenone inhibits [Ca2+] accumulation in HT22 cells and has antioxidantive activity.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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    99.38% (May vary between batches)

    708-53-2

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2,3-Dihydroxy-4-methoxyacetophenone (orb1217711)

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200 mg
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