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4-MMPB

SKU: orb1298626

Description

4-MMPB is a selective 15-lipoxygenase (15-LOX-1) inhibitor with IC50 values of ~19 µM against both soybean and human enzymes. It serves as a research tool for studying the role of 15-LOX-1 in pathways relevant to prostate cancer and other inflammation-associated diseases in cellular models.

Research Area

Cell Biology, Metabolism Research

Images & Validation

Key Properties

CAS Number928853-86-5
MW313.42
Purity98.75% (May vary between batches)
FormulaC16H19N5S
SMILESCN1CCN(CC1)c1nc(C)c2Nc3ccccc3Sc2n1
TargetApoptosis,Lipoxygenase
SolubilityDMSO:8 mg/mL (25.52 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (1.6 mM)

Bioactivity

Target IC50
Others:69.6 μM
In Vitro
15-Lipoxygenase Inhibitor 1 has an IC50 of 69.6 μM for DPPH bleaching;15-Lipoxygenase Inhibitor 1 (41.48 μM; 72 hours) induces apoptosis and DNA damage in PC-3 Cells.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, inhibit, LOX, Lipoxygenase, inhibition, 4MMPB, 4-MMPB, 4 MMPB, 15-Lipoxygenase Inhibitor 1, Apoptosis, cancer, radical, scavenging

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    C16H19N5S

    1 g, 500 mg, 200 mg, 5 mg, 10 mg, 25 mg, 100 mg, 50 mg
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Key Properties

No computed properties available.

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4-MMPB (orb1298626)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

2 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 100.00
5 mg
$ 100.00
10 mg
$ 130.00
25 mg
$ 210.00
50 mg
$ 320.00
100 mg
$ 490.00
200 mg
$ 680.00
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