APJ receptor agonist 8

SKU: orb2566969

Description

APJ receptor agonist 8 is a small molecule agonist of the APJ receptor, enhancing load-independent cardiac contractility in isolated perfused rat hearts. It mimics the action of the endogenous ligand Apelin and has an EC50 of 21.5 µM.

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	2049973-39-7
MW	525.58
Purity	98.31%
Formula	C₂₄H₂₇N₇O₅S
SMILES	N(S([C@H]([C@H](O)C=1N=CC(C)=CN1)C)(=O)=O)C=2N(C(=NN2)C=3N=C(C)C=CC3)C4=C(OC)C=CC=C4OC
Target	Apelin receptor

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

Apelin receptor

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