(-)-Apomorphine hydrochloride hydrate

SKU: orb2283774

Description

(-)-Apomorphine hydrochloride hydrate is a broad-spectrum dopamine agonist and ferroptosis inhibitor with high affinity for D1-like receptors. It serves as a research tool for studying mitochondrial disorders, Parkinson's disease models, and cell death mechanisms in both in vitro and in vivo experimental systems.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	58117-94-5
MW	303.8
Formula	C₁₇H₁₈ClNO₂. xH₂O
SMILES	OC1=C(O)C=CC2=C1C3=C([C@@H](C2)N(C)CC4)C4=CC=C3.Cl. xH2O
Target	Ferroptosis,Dopamine Receptor

Bioactivity

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In Vitro

(-)-Apomorphine hydrochloride hydrate prevented ferroptosis in fibroblasts from various types of mitochondrial diseases as well as in normal controls. (-)-Apomorphine hydrochloride hydrate induced significant downregulation of PTSG2 and suppressed lipid peroxide to the same extent as other inhibitors of ferroptosis also indicate that (-)-Apomorphine hydrochloride hydrate suppresses ferroptosis.

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Ferroptosis, DopamineReceptor, Dopamine Receptor

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Compound Identifiers

PubChem CID

6852399 ↗

Key Properties

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No computed properties available.

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