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APY0201

SKU: orb1226721

Description

APY0201 is a potent, highly selective, ATP-competitive PIKfyve inhibitor (IC50=5.2 nM) that interrupts the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3,5)P2; a unique small molecular IL-12/23 production inhibitor.

Images & Validation

Key Properties

CAS Number1232221-74-7
MW413.48
Purity>98% (HPLC)
FormulaC23H23N7O
SMILESCC1=CC(/C=N/NC2=NC3=CC(C4=CC=NC=C4)=NN3C(N5CCOCC5)=C2)=CC=C1
TargetPI3K
SolubilityDMSO: 10 mM

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

APY0201 | APY-0201 | APY 0201

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    1232221-74-7

    413.48

    C23H23N7O

    10 mg, 25 mg, 50 mg, 2 mg, 5 mg
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Protocol Information

APY0201 (orb1226721)

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% DMSO +
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Available Sizes

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100 mg
200 mg
500 mg
2 mg
$ 120.00
5 mg
$ 170.00
10 mg
$ 280.00
25 mg
$ 480.00
50 mg
$ 780.00