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APY0201

SKU: orb1705533

Description

APY0201 is a potent and selective ATP-competitive inhibitor of PIKfyve with an IC50 of 5.2 nM, blocking the synthesis of PtdIns(3,5)P2 from PtdIns3P. It is a valuable research tool for studying lysosomal biology, autophagy, and cellular trafficking in both in vitro and in vivo models.

Research Area

Immunology & Inflammation, Signal Transduction

Images & Validation

Key Properties

CAS Number1232221-74-7
MW413.48
Purity99.74%
FormulaC23H23N7O
SMILESCc1cccc(\C=N\Nc2cc(N3CCOCC3)n3nc(cc3n2)-c2ccncc2)c1
TargetPI3K,Interleukin
SolubilityDMSO:1 mg/mL (2.42 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.42 mM)

Bioactivity

Target IC50
PIKfyve:5.2 nM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

PIKfyve, Interleukin Related, Interleukin, Fab1, inhibit, Inhibitor, APY 0201, APY0201, APY-0201

Similar Products

  • APY0201 [orb1226721]

    >98% (HPLC)

    1232221-74-7

    413.48

    C23H23N7O

    1 g, 500 mg, 200 mg, 100 mg, 5 mg, 10 mg, 25 mg, 50 mg, 2 mg
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Key Properties

No computed properties available.

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Protocol Information

APY0201 (orb1705533)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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2 mg
$ 120.00
5 mg
$ 150.00
10 mg
$ 240.00
25 mg
$ 390.00
50 mg
$ 630.00
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