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BMS-195614

SKU: orb1785921

Description

BMS-195614 is a potent, orally bioavailable RARα antagonist (Ki = 2.5 nM) that modulates multiple signaling pathways. It upregulates Bcl2 expression while suppressing NF-κB, AP-1, and PPAR transactivation. Additionally, it reduces IL-6 and VEGF production, mitigates phototoxic damage from blue light, and exhibits anti-migratory, anti-inflammatory, and anti-angiogenic properties.

Images & Validation

Key Properties

CAS Number182135-66-6
MW448.512467384338
Purity>98%
FormulaC29H24N2O3
SMILESCC1(C)CC=C(C2=CN=C3C=CC=CC3=C2)C4=C1C=CC(=C4)C(=O)NC5=CC=C(C=C5)C(=O)O

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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    1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg
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Key Properties

No computed properties available.

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Protocol Information

BMS-195614 (orb1785921)

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100 mg
$ 890.00
250 mg
$ 1,510.00
1 g
$ 3,110.00
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