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bruceine B

SKU: orb1220748

Description

Bruceine B a potent inhibitor of leukocyte-endothelial cell adhesion may have anti-inflammatory activity it can inhibit neutrophil adhesion to lipopolysaccharide-stimulated HUVEC and T cell adhesion to TNF-stimulated HUVEC.

Images & Validation

Key Properties

CAS Number25514-29-8
MW480.5
Purity>98% (HPLC)
FormulaC23H28O11
SMILES[H][C@]12[C@@H](OC(C)=O)C(=O)O[C@]3([H])C[C@@]4([H])C(C)=C(O)C(=O)C[C@]4(C)[C@@]4([H])[C@@H](O)[C@H](O)[C@]1(OC[C@@]234)C(=O)OC
TargetTNF

Bioactivity

In Vitro
Bruceine B exhibits an IC50 of 10 nM for antimalarial activity.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • bruceine B [orb3027291]

    99.85%

    25514-29-8

    480.5

    C23H28O11

    25 mg, 1 mg, 10 mg, 5 mg, 50 mg
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bruceine B (orb1220748)

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