Carbobenzoxyphenylalanine

SKU: orb1219349

Description

Carbobenzoxyphenylalanine is a thermolysin inhibitor.The protease can be inhibited by the serine specific reagents phenylmethanesulfonyl fluoride and diisopropyl fluorophosphate and the alkylating reagent, carbobenzoxyphenylalanine chloromethyl ketone, in the presence of organic solvents at 1 mM concentration. The inhibitions of chromatin-bound protease in rat liver by these compounds are irreversible. On the other hand, carbobenzoxyphenylalanine and p-nitrophenyl acetate were shown to be reversible inhibitors of rat liver chromatin-bound protease.

Images & Validation

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Key Properties

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CAS Number	1161-13-3
MW	299.32
Purity	>98% (HPLC)
Formula	C₁₇H₁₇NO₄
SMILES	C1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2=CC=CC=C2
Target	thermolysin
Solubility	DMSO:Soluble

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Carbobenzoxy-L-phenylalanine,NSC 402059,NSC-402059

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Gene Symbol

thermolysin

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