Cart summary

You have no items in your shopping cart.

Ceefourin 1

SKU: orb1219913

Description

Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.Ceefourin 1 and Ceefourin 2, that inhibit transport of a broad range of MRP4 substrates, yet are highly selective for MRP4 over other ABC transporters, including P-glycoprotein (P-gp), ABCG2 (Breast Cancer Resistance Protein; BCRP) and MRP1 (multidrug resistance protein 1; ABCC1). Both compounds are more potent MRP4 inhibitors in cellular assays than the most widely used inhibitor, MK-571, requiring lower concentrations to effect a comparable level of inhibition. Furthermore, Ceefourin 1 and Ceefourin 2 have low cellular toxicity, and high microsomal and acid stability.

Images & Validation

Key Properties

CAS Number315702-40-0
MW294.42
Purity>98% (HPLC)
FormulaC11H10N4S3
SMILESS=C1N(C)C(CSC2=NC3=CC=CC=C3S2)=NN1
TargetMRP
SolubilityIn Vitro: DMSO : 125 mg/mL (424.56 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • Ceefourin 1 [orb1298798]

    99.15% (May vary between batches)

    315702-40-0

    294.42

    C11H10N4S3

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 1 ml x 10 mM (in DMSO), 1 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

Ceefourin 1 (orb1219913)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

200 mg
500 mg
2 mg
$ 100.00
5 mg
$ 140.00
10 mg
$ 190.00
25 mg
$ 370.00
50 mg
$ 550.00
100 mg
$ 790.00