Cefazolin sodium

SKU: orb1310135

Description

Cefazolin sodium is a first-generation cephalosporin antibiotic that exerts its bactericidal effect by binding to penicillin-binding proteins (PBPs). This action inhibits bacterial cell wall synthesis, leading to cell lysis. It is widely used in research for studying antimicrobial mechanisms and efficacy in both in vitro and in vivo models against susceptible Gram-positive bacteria.

Research Area

Infectious Disease & Virology

Images & Validation

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Key Properties

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CAS Number	27164-46-1
MW	476.48
Purity	98.38%
Formula	C₁₄H₁₃N₈NaO₄S₃
SMILES	[Na+].Cc1nnc(s1)SCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)Cn2nnnc2)SC1)C(=O)[O-]
Target	Antibacterial,Antibiotic
Solubility	Ethanol:< 1 mg/mL (insoluble or slightly soluble);DMSO:50 mg/mL (104.94 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.2 mM)

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Cephazolin, cephazolin sodium, Cefazolin sodium salt, cefazoline sodium, Cefazolin, Cefazolin sodium, C8-B4, Bacterial, Ancef, Antibiotic, anti-inflammatory activity, NK-92, PBPs, PBMC, inhibit, Inhibitor, Sodium cefazolin, Sodium cephazolin, POCD, Peptidoglycan synthase, post-operative cognitive dysfunction, PON, TF-1

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Compound Identifiers

PubChem CID

23675322 ↗

Key Properties

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No computed properties available.

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