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Dexpramipexole

SKU: orb1679027

Description

Dexpramipexole

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number104632-28-2
MW211.33
Purity99.78%
FormulaC10H17N3S
SMILESNC1=NC2=C(C[C@H](NCCC)CC2)S1
TargetDopamine Receptor
SolubilityDMSO:8 mg/mL (37.86 mM)

Bioactivity

In Vitro
Dexpramipexole is neur Protective and has been used in research studies fo the treatment of amyotrophic lateral sclerosis (ALS). Dexpramipexole reduces mitochondrial Reactive oxygen species (ROS) production, inhibits activation of apoptotic pathways, and improves cell survival in response to a variety of neurotoxins and beta-amyloid neurotoxicity. Dexpramipexole is much less active than dopamine agonists o the S-(-) isomer.

Storage & Handling

Storagekeep away from direct sunlight,store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

KNS 760704, Dexpramipexole, Dopamine Receptor, Dopamine, DopamineReceptor, Pramipexole, R-Pramipexole

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Key Properties

No computed properties available.

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Dexpramipexole (orb1679027)

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Available Sizes

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2 mg
$ 70.00
5 mg
$ 90.00
10 mg
$ 120.00
25 mg
$ 190.00
50 mg
$ 270.00
100 mg
$ 370.00
200 mg
$ 530.00
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