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EC5026

SKU: orb1219297

Description

EC5026 has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators. EC5026 (BPN-19186) is a first-in-class, small molecule that potently inhibits soluble Epoxide Hydrolase (sEH), a key regulatory enzyme involved in the metabolism of membrane fatty acids. Inhibition of sEH treats pain by stabilizing natural analgesic and anti-inflammatory mediators. sEH inhibitors developed by EicOsis have already shown efficacy for treating pain with no apparent adverse or addictive effects in laboratory animals and relieving naturally occurring pain in dogs, cats and horses.

Images & Validation

Key Properties

CAS Number1809885-32-2
MW405.39
Purity>98% (HPLC)
FormulaC18H23F4N3O3
SMILESO=C(NC1CCN(C([C@@H](C)CC)=O)CC1)NC2=CC=C(OC(F)(F)F)C(F)=C2
TargetsEH
SolubilityDMSO:250 mg/mL (616.69 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

BPN-19186

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Protocol Information

EC5026 (orb1219297)

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% DMSO +
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% Tween 80 +
%

Available Sizes

Select a size below

200 mg
500 mg
2 mg
$ 90.00
5 mg
$ 130.00
10 mg
$ 190.00
25 mg
$ 300.00
50 mg
$ 500.00
100 mg
$ 730.00