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F594-1001

SKU: orb2564314

Description

F594-1001 (compound 6) serves as a potent, highly selective inhibitor of SARS-CoV-2 Mac1-ADP-ribose, displaying IC 50 values of 8.5 μM, 68 μM, and 45 μM in AS, FP, and FRET assays, respectively. It binds directly to SARS-CoV-2 Mac1 and demonstrates dose-dependent inhibition of Mac1 ADP-ribosylhydrolase activity.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number1215326-44-5
MW445.94
FormulaC23H28ClN3O4
SMILESO=C(C=1C=C(OC)C=C(OC)C1)N(CC=2C=CC=C(Cl)C2)CCC(=O)N3CCNCC3
TargetSARS-CoV

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

F594-1001 (orb2564314)

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