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FOY 251

SKU: orb1219783

Description

FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.FOY-251, an active metabolite of camostat mesilate, on sodium transport in the mouse cortical collecting duct cell line (M-1 cells) and on blood pressure in Dahl salt-sensitive rats. Treatment with camostat mesilate or FOY-251 decreased equivalent current (Ieq) in M-1 cells in a dose-dependent manner and inhibited the protease activity of prostasin in vitro.

Images & Validation

Key Properties

CAS Number71079-09-9
MW409.41
Purity>98% (HPLC)
FormulaC17H19N3O7S
SMILESCS(O)(=O)=O.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CC(O)=O)cc1
Targetproteinase
SolubilityIn Vitro: DMSO : 20 mg/mL (48.85 mMul)

Bioactivity

In Vitro
FOY-251 represents a dose-dependent inhibition of equivalent current in M-1 cells. FOY-251 inhibits the proteolytic activity of prostasin.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

FOY 251 (orb1219783)

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Available Sizes

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5 mg
$ 280.00
10 mg
$ 450.00
25 mg
$ 740.00
50 mg
$ 1,040.00
100 mg
$ 1,460.00
500 mg
$ 2,870.00