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GS-621763

SKU: orb1303281

Description

GS-621763 is a prodrug of the antiviral nucleoside GS-441524, demonstrating efficacy against SARS-CoV-2. It has shown promising antiviral activity in both in vitro cellular assays and in vivo models of COVID-19 pathogenesis, supporting its investigation as a research tool for coronavirus therapeutics.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number2647442-13-3
MW501.53
Purity99.52% (May vary between batches)
FormulaC24H31N5O7
SMILESCC(C)C(=O)OC[C@H]1O[C@](C#N)([C@H](OC(=O)C(C)C)[C@@H]1OC(=O)C(C)C)c1ccc2c(N)ncnn12
TargetSARS-CoV
SolubilityDMSO:100 mg/mL (199.39 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.98 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

GS 621763, GS621763, GS-621763, inhibit, Inhibitor, SARS coronavirus, SARS-CoV-2, SARS-CoV, SARSCoV

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Key Properties

No computed properties available.

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Protocol Information

GS-621763 (orb1303281)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 110.00
5 mg
$ 200.00
1 ml x 10 mM (in DMSO)
$ 210.00
10 mg
$ 290.00
25 mg
$ 560.00
50 mg
$ 780.00
100 mg
$ 1,030.00
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