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Guvacine

SKU: orb1684555

Description

Guvacine is a natural alkaloid that selectively inhibits GABA transporters (GATs). This psychoactive lead compound is used in neuroscience research to study GABAergic neurotransmission in both in vitro and in vivo models of neurological and psychiatric disorders.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number498-96-4
MW127.14
Purity99.95%
FormulaC6H9NO2
SMILESO=C(O)C1=CCCNC1
TargetGABA Receptor

Bioactivity

Target IC50
GAT-2 (rat):58 μM|GAT-1 (rat):39 μM|GAT-1 (human):14 μM|GAT-3 (rat):378 μM|BGT3 (human):1870 μM|GAT-3 (human):119 μM

Storage & Handling

Storagekeep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

GABA, GABA Receptor, GABAReceptor, Guvacine

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Key Properties

No computed properties available.

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Guvacine (orb1684555)

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20 mg
$ 370.00
DispatchUsually dispatched within 5-10 working days
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