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HSP27 inhibitor J2

SKU: orb1225668

Description

HSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27, induces significant abnormal HSP27 dimer formation in cancer cells; enhances cancer cell sensitization with cisplatin, cisplatin-induced lung cancer cell growth inhibition in vitro; significantly inhibits immune cell infiltration in lung tissue, attenuates radiation-induced pulmonary inflammation in mice.

Images & Validation

Key Properties

CAS Number2133499-85-9
MW264.295
Purity>98% (HPLC)
FormulaC13H12O4S
SMILESO=C1C=C(C)OC2=C1C(O)=CC(OCC3SC3)=C2
TargetHSP
SolubilityIn Vitro: DMSO : 20 mg/mL (75.67 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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HSP27 inhibitor J2 (orb1225668)

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Available Sizes

Select a size below

200 mg
500 mg
2 mg
$ 280.00
5 mg
$ 450.00
10 mg
$ 670.00
25 mg
$ 1,040.00
50 mg
$ 1,460.00
100 mg
$ 1,930.00