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JAK-IN-1

SKU: orb1709379

Description

JAK-IN-1 is a potent, cell-permeable inhibitor of JAK kinases, demonstrating a favorable selectivity profile with IC50 values of 0.26 nM (JAK1), 0.8 nM (JAK2), and 3.2 nM (JAK3). It is a valuable chemical tool for investigating JAK-STAT signaling in cellular and biochemical assays relevant to immunology and oncology research.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1334673-53-8
MW380.44
FormulaC20H24N6O2
SMILESCC(C)(C)[C@@H](NC(=O)c1c[nH]c2ncc(nc12)C1CC1)C(=O)N1CC(C1)C#N
TargetJAK,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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JAK-IN-1 (orb1709379)

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