Lazertinib mesylate

SKU: orb3027911

Description

Lazertinib (mesylate) (YH25448 (mesylate); GNS-1480 (mesylate)) is an orally active EGFR inhibitor capable of crossing the blood-brain barrier. It suppresses the p-EGFR, p-AKT, and p-ERK signaling pathways, leading to apoptosis. Lazertinib (mesylate) demonstrates antitumor activity in the H1975-luc BM xenograft model in mice and is applicable for researching non-small cell lung cancer.

Images & Validation

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Key Properties

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CAS Number	2247995-37-3
MW	650.75
Formula	C₃₁H₃₈N₈O₆S
SMILES	O=C(C=C)NC1=CC(NC2=NC=CC(=N2)N3N=C(C=4C=CC=CC4)C(=C3)CN(C)C)=C(OC)C=C1N5CCOCC5.O=S(=O)(O)C
Target	EGFR,Akt,ERK

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

EGFR,Akt,ERK

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