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Loxapine

SKU: orb1306268

Description

Loxapine is a dibenzoxazepine antipsychotic that acts as a D2/D4 dopamine receptor inhibitor and serotonergic antagonist. It is used in schizophrenia research and has been applied in both in vitro receptor binding assays and in vivo behavioral models to study its pharmacological profile.

Research Area

Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1977-10-2
MW327.81
Purity99.98%
FormulaC18H18ClN3O
SMILESCN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12
Target5-HT Receptor,Dopamine Receptor,Antibacterial
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.1 mM);DMSO:32.33 mg/mL (98.62 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

D4, D2, DopamineReceptor, Dopamine Receptor, 5-HT2 (bovine), 5-HT2 (human), 5-HT Receptor, 5HTReceptor, 5HT Receptor, 5-hydroxytryptamine Receptor, antipsychotics, inhibit, Inhibitor, Loxapine, IL-2, IL-1β, schizophrenia, serotonin, Serotonin Receptor

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Key Properties

No computed properties available.

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Loxapine (orb1306268)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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25 mg
$ 80.00
50 mg
$ 90.00
100 mg
$ 110.00
1 ml x 10 mM (in DMSO)
$ 120.00
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