Methyl cinnamate

SKU: orb1220924

Description

Methyl cinnamate a tyrosinase inhibitor and a flavoring compound has antimicrobial antiadipogenic vasorelaxant and anti-inflammatory effects.(In Vitro):In 3T3-L1 cell model, Methyl cinnamate (Methyl 3-phenylpropenoate) inhibits adipocyte differentiation by attenuating expression of the adipogenic transcription factors SREBP-1, PPARγ, and C/EBPα and the transcriptional activity of PPARγ. In addition, Methyl cinnamate (Methyl 3-phenylpropenoate) activates the CaMKK2 AMPK signaling cascade involved in the regulation of adipogenesis.

Images & Validation

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Key Properties

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CAS Number	103-26-4
MW	162.19
Purity	>98% (HPLC)
Formula	C₁₀H₁₀O₂
SMILES	COC(=O)\C=C\c1ccccc1
Target	Tyrosinase
Solubility	DMSO: 30 mg/mL (184.97 mM);Water: Insoluble

Bioactivity

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In Vitro	In 3T3-L1 cell model, Methyl cinnamate (Methyl 3-phenylpropenoate) inhibits adipocyte differentiation by attenuating expression of the adipogenic transcription factors SREBP-1, PPARγ, and C/EBPα and the transcriptional activity of PPARγ. In addition, Methyl cinnamate (Methyl 3-phenylpropenoate) activates the CaMKK2 AMPK signaling cascade involved in the regulation of adipogenesis. Read more...

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Tyrosinase

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