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Methyl cinnamate

SKU: orb1220924

Description

Methyl cinnamate a tyrosinase inhibitor and a flavoring compound has antimicrobial antiadipogenic vasorelaxant and anti-inflammatory effects.(In Vitro):In 3T3-L1 cell model, Methyl cinnamate (Methyl 3-phenylpropenoate) inhibits adipocyte differentiation by attenuating expression of the adipogenic transcription factors SREBP-1, PPARγ, and C/EBPα and the transcriptional activity of PPARγ. In addition, Methyl cinnamate (Methyl 3-phenylpropenoate) activates the CaMKK2 AMPK signaling cascade involved in the regulation of adipogenesis.

Images & Validation

Key Properties

CAS Number103-26-4
MW162.19
Purity>98% (HPLC)
FormulaC10H10O2
SMILESCOC(=O)\C=C\c1ccccc1
TargetTyrosinase
SolubilityDMSO: 30 mg/mL (184.97 mM);Water: Insoluble

Bioactivity

In Vitro
In 3T3-L1 cell model, Methyl cinnamate (Methyl 3-phenylpropenoate) inhibits adipocyte differentiation by attenuating expression of the adipogenic transcription factors SREBP-1, PPARγ, and C/EBPα and the transcriptional activity of PPARγ. In addition, Methyl cinnamate (Methyl 3-phenylpropenoate) activates the CaMKK2 AMPK signaling cascade involved in the regulation of adipogenesis.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information