Methyl cinnamate

SKU: orb1301699

Description

Methyl cinnamate is a naturally occurring flavor compound that acts as a tyrosinase inhibitor. It exhibits a range of biological activities, including antimicrobial, anti-inflammatory, and vasorelaxant effects, making it a useful small molecule for research in dermatology, cardiovascular studies, and metabolic disease models.

Research Area

Epigenetics & Chromatin, Infectious Disease & Virology, Protein Biochemistry, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	103-26-4
MW	162.19
Purity	99.95%
Formula	C₁₀H₁₀O₂
SMILES	COC(=O)\C=C\c1ccccc1
Target	Tyrosinase,Antibacterial,AMPK
Solubility	DMSO:50 mg/mL (308.28 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (12.33 mM);H2O:Insoluble

Bioactivity

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In Vitro

At 1-3000 μmol/L, the E-isomer of methyl cinnamate (E-MC) concentration-dependently relaxed endothelium-intact aortic preparations that had been precontracted with phenylephrine (PHE; 1 μmol/L), with an IC50 value (geometric mean) of 877.6 μmol/L (95% confidence interval (CI) 784.1-982.2 μmol/L). Over the concentration range 1-3000 μmol/L, E-MC relaxed K(+) -induced contractions in mesenteric artery preparations (IC50 314.5 μmol/L; 95% CI 141.9-697.0 μmol/L) with greater potency than in aortic preparations (IC50 1144.7 μmol/L; 95% CI 823.2-1591.9 μmol/L).

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Methyl cinnamate, Methyl 3-phenylpropenoate, natural, inhibit, Inhibitor, flavor, activation, 3T3-L1, AMPK, AMP-activated protein kinase, antimicrobial, Bacterial, C/EBPα, CaMKK2, cells, SREBP-1, PPARγ, preadipocytes, Tyrosinase

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Compound Identifiers

PubChem CID

637520 ↗

Key Properties

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No computed properties available.

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