Metoclopramide hydrochloride hydrate

SKU: orb1298978

Description

Metoclopramide hydrochloride hydrate is a dopamine D2 receptor antagonist utilized in research for its antiemetic and gastroprokinetic properties. It is commonly applied in studies of gastrointestinal motility, emesis, and dopaminergic signaling in both in vitro and in vivo experimental models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	54143-57-6
MW	354.27
Purity	99.33% (May vary between batches)
Formula	C₁₄H₂₅Cl₂N₃O₃
SMILES	O.Cl.CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC
Target	Dopamine Receptor,5-HT Receptor
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.65 mM);DMSO:50 mg/mL (141.14 mM)

Bioactivity

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Target IC50	5-HT3 receptor:308 nM (IC50)\|D2 receptor:483 nM (IC50)

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Serotonin Receptor, reflux, vomiting, Dopamine Receptor, Dopamine, DopamineReceptor, D2, 5HTReceptor, 5-hydroxytryptamine Receptor, 5-HT Receptor, 5HT Receptor, Inhibitor, gastro-oesophageal, gastroparesis, nausea, Metoclopramide monohydrochloride Monohydrate, Metoclopramide monohydrochloride monohydrate, Metoclopramide, Metoclopramide hydrochloride, Metoclopramide hydrochloride hydrate, Metoclopramide hydrochloride Hydrate, inhibit

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Compound Identifiers

PubChem CID

441347 ↗

Key Properties

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No computed properties available.

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