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Metoprine

SKU: orb1219949

Description

Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.In mammals, histamine N-methyltransferase (HMT) is the sole enzyme responsible for degrading histamine in the brain. Metoprine, one of the most potent HMT inhibitors, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT. Consequently, this compound can be a candidate for a prototype of drugs for the treatment of METH overdose.

Images & Validation

Key Properties

CAS Number7761-45-7
MW269.13
Purity>98% (HPLC)
FormulaC11H10Cl2N4
SMILESCc1nc(N)nc(N)c1-c1ccc(Cl)c(Cl)c1
TargetHistamine Receptor
SolubilityIn Vitro: DMSO : 20.83 mg/mL (77.40 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • Metoprine [orb1298843]

    99.09%

    7761-45-7

    269.13

    C11H10Cl2N4

    10 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO), 25 mg, 5 mg, 500 mg
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Metoprine (orb1219949)

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Available Sizes

Select a size below

5 mg
$ 100.00
10 mg
$ 150.00
25 mg
$ 240.00
50 mg
$ 370.00
100 mg
$ 540.00
500 mg
$ 1,200.00