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MKT-077

SKU: orb1226208

Description

MKT-077 (FJ-776) is a highly water-soluble (>200 mg/ml) rhodacyanine dye that exhibits significant antitumor activity, binds to Hsp70 family member, mortalin (mot-2), and abrogates its interactions with p53; induces release of wild-type p53 from cytoplasmically sequestered p53-mot-2 complexes and rescued its transcriptional activation function; also is a potent telomerase inhibitor with IC50 of 5 uM.

Images & Validation

Key Properties

CAS Number147366-41-4
MW432
Purity>98% (HPLC)
FormulaC21H22ClN3OS2
SMILESO=C1N(CC)/C(S/C1=C2SC3=CC=CC=C3N/2C)=C/C4=CC=CC=[N+]4CC.[Cl-]
TargetHSP
SolubilityDMSO: 20 mg/mL; Water: 20 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

FJ-776

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MKT-077 (orb1226208)

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% DMSO +
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Available Sizes

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200 mg
500 mg
5 mg
$ 140.00
10 mg
$ 220.00
25 mg
$ 360.00
50 mg
$ 550.00
100 mg
$ 710.00