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ML-346

SKU: orb1227168

Description

A novel activator of HSP70 with EC50 of 4.6 uM; induces HSF-1-dependent chaperone expression and restores protein folding in conformational disease models, which are mediated by novel mechanisms involving FOXO, HSF-1, and Nfr-2.

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Key Properties

CAS Number100872-83-1
MW272.2561
Purity>98% (HPLC)
FormulaC14H12N2O4
SMILESO=C(NC(NC/1=O)=O)C1=C\C=C\C2=CC=C(OC)C=C2
TargetHSP
SolubilityDMSO: ≥ 29 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ML346

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Protocol Information

ML-346 (orb1227168)

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% DMSO +
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Available Sizes

Select a size below

2 mg
$ 90.00
5 mg
$ 130.00
10 mg
$ 180.00
25 mg
$ 260.00
50 mg
$ 400.00
100 mg
$ 610.00
500 mg
$ 1,290.00