Moracin C

SKU: orb1684403

Description

Moracin C is a natural anti-inflammatory compound isolated from Morus species. It functions by inhibiting LPS-induced nitric oxide (NO) and reactive oxygen species (ROS) production in vitro, making it a useful research tool for studying inflammatory pathways and oxidative stress.

Research Area

Immunology & Inflammation, Metabolism Research, Neuroscience, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	69120-06-5
MW	310.34
Purity	>99.99% (May vary between batches)
Formula	C₁₉H₁₈O₄
SMILES	CC(C)=CCc1c(O)cc(cc1O)-c1cc2ccc(O)cc2o1
Target	Reactive Oxygen Species,ROS,COX,NO Synthase
Solubility	10% DMSO+90% Saline:3.3 mg/mL (10.63 mM);DMSO:225 mg/mL (725.01 mM)

Bioactivity

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Target IC50	S. aureus:32 µg/mL(MIC)\|FabI (S. aureus):83.8 µM
In Vivo	Moracin C (100 mg/kg, gavage, mice) is rapidly and well absorbed in the intestinal tract and is widely distributed in the gastrointestinal tract, liver, kidney and lungs.
In Vitro	Moracin C (1-50 μM, 24 h) inhibited the release of LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) from RAW264.7 cells. Moracin C (1-50 μM, 2 h) inhibits mRNA and protein expression of iNOS and COX-2 in RAW264.7 cells. Moracin C (1-50 μM, 2 h) inhibits the production of pro-inflammatory cytokines (IL-1β, IL-6 and TNF-α) in LPS-activated RAW 264.7 cells . Moracin C (1-50 μM, 2 h) inhibits the phosphorylation of p38, ERK and JNK in LPS-activated RAW 264.7 cells.

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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COX, Moracin C, NOSynthase, NOS, NO, NO Synthase, ROS

Quality Guarantee

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Compound Identifiers

PubChem CID

155248 ↗

Key Properties

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No computed properties available.

Protocol Information

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Purity:	98.0%（HPLC）
CAS Number:	69120-06-5

CAS Number:	1146113-27-0
MW:	340.37
Formula:	C₂₀H₂₀O₅

Purity:	>98% (HPLC)
CAS Number:	69120-06-5
MW:	310.34
Formula:	C₁₉H₁₈O₄

Moracin C

Description

Research Area

Images & Validation

Key Properties

Bioactivity

Storage & Handling

Alternative Names

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