Cart summary

You have no items in your shopping cart.

MYCi975

SKU: orb1219642

Description

MYCi975 is an orally active inhibitor of MYC.MYCi975 inhibits P493-6, MV411,SK-N-B2 cells viability in an MYC-dependent manner(IC50s of 3.7, 3.9, 6.4 μM, respectively).The initial lead, MYC inhibitor 361 (MYCi361), suppressed in vivo tumor growth in mice, increased tumor immune cell infiltration, upregulated PD-L1 on tumors, and sensitized tumors to anti-PD1 immunotherapy. However, 361 demonstrated a narrow therapeutic index.

Images & Validation

Key Properties

CAS Number2289691-01-4
MW561.3
Purity>98% (HPLC)
FormulaC25H16Cl2F6N2O2
TargetMYC

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
DisclaimerFor research use only

Similar Products

  • MYCi975 [orb1709073]

    99.30%

    2289691-01-4

    561.3

    C25H16Cl2F6N2O2

    25 mg, 5 mg, 10 mg, 50 mg, 1 mg, 1 ml x 10 mM (in DMSO)
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

MYCi975 (orb1219642)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

5 mg
$ 380.00
10 mg
$ 600.00
25 mg
$ 980.00
50 mg
$ 1,340.00
100 mg
$ 1,800.00
500 mg
$ 3,470.00