neo-gambogic acid

SKU: orb1220670

Description

Neogambogic acid an active ingredient in garcinia can inhibit the growth of some solid tumors and result in an anticancer effect it may be responsible for the inhibition of proliferation of human breast cancer cell line MCF-7 cells.

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Key Properties

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CAS Number	93772-31-7
MW	646.8
Purity	>98% (HPLC)
Formula	C₃₈H₄₆O₉?
SMILES	C\C(C)=C\CCC1(C)CC(O)c2c(O)c3C(=O)C4=CC5CC6C(C)(C)OC(C\C=C(/C)C(O)=O)(C5=O)C46Oc3c(C\C=C(/C)C)c2O1
Target	Others

Bioactivity

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In Vivo	Neogambogic acid arrests A549-induced tumor growth in nude mice.
In Vitro	Neogambogic acid inhibits HCT-8, Bel-7402, BGC-823, A549, and A2780 cell proliferation, with an IC50 between 1.75 and 3 μM. Neogambogic acid induces A549 cells apoptosis arrested the cells to G0/G1 phase in vitro. Read more...

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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