Cart summary

You have no items in your shopping cart.

p38α inhibitor 6

SKU: orb3028194

Description

p38α inhibitor6 (compound 19) is a p38α inhibitor with an IC50 value of 0.68 μM. It induces apoptosis, arrests the cell cycle in the G0 and G2/M phases, reduces TNF-α concentration, upregulates the expression of the tumor suppressor gene p53, increases the Bax/BCL-2 ratio, and activates caspase3/7.

Research Area

Cell Biology, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

TargetApoptosis,Caspase,MDM-2/p53,Bcl-2 Family,p38 MAPK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • Adezmapimod [orb1307506]

    99.93%

    152121-47-6

    377.43

    C21H16FN3OS

    10 mg, 500 mg, 1 ml x 10 mM (in DMSO), 25 mg, 50 mg, 100 mg, 5 mg
  • L-167307 [orb1703174]

    188352-45-6

    376.45

    C22H17FN2OS

    50 mg, 100 mg, 25 mg
  • Talmapimod hydrochloride [orb1708559]

    309915-12-6

    549.46

    C27H31Cl2FN4O3

    25 mg, 50 mg, 100 mg
  • SKF-86002 [orb1305588]

    99.85% (May vary between batches)

    72873-74-6

    297.35

    C16H12FN3S

    5 mg, 10 mg, 50 mg, 25 mg, 100 mg, 200 mg
  • Oxidopamine hydrochloride [orb1309284]

    99.85% (May vary between batches)

    28094-15-7

    205.64

    C8H12ClNO3

    5 mg, 50 mg, 100 mg, 10 mg, 25 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

p38α inhibitor 6 (orb3028194)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%