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PD-L1-IN-1

SKU: orb1688462

Description

PD-L1-IN-1 is a potent small molecule inhibitor of PD-L1 (IC50 = 115 nM). It blocks the PD-1/PD-L1 interaction, enhancing T-cell-mediated killing of cancer cells like PC9 and HCC827 in vitro by increasing IFN-γ release and inducing apoptosis, with research applications in immuno-oncology.

Research Area

Cell Biology, Immunology & Inflammation

Images & Validation

Key Properties

MW377.44
FormulaC21H23N5O2
TargetApoptosis,Others,PD-1/PD-L1

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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PD-L1-IN-1 (orb1688462)

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