SARS-CoV-2 (COVID-19) NSP8 Protein

SKU: orb640164

Description

NSP8, forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. By investigating the entire proteome of SARS-CoV-2, six proteins, including the S protein and five non-structural proteins (nsp3, 3CL-pro, and nsp8-10) were predicted to be adhesins, which are crucial to the viral adhering and host invasion. The S, nsp3, and nsp8 proteins were also predicted by Vaxign-ML to induce high protective antigenicity.

Images & Validation

−

Application Notes	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 23.9 kDa. The protein migrates as 22-25 kDa under reducing (R) condition (SDS-PAGE).

Key Properties

−

Source	SARS-CoV-2 NSP8, His Tag (orb640164) is expressed from E. coli cells. It contains AA Ala 1 - Gln 198 (Accession # YP_009725304.1).
Expression System	E. coli
Target	NSP8
Reactivity	Virus
Tag	N-10×His
Molecular Weight	23.9 kDa
Expression Region	Ala 1 - Gln 198
Purity	95%
Endotoxins	1.0 EU per μg
Conjugation	Unconjugated

Storage & Handling

−

Storage	-70℃
Form/Appearance	Liquid
Buffer/Preservatives	20 mM Tris, 250 mM NaCl, pH8.5
Dry Ice Shipping	Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
Disclaimer	For research use only

Alternative Names

−

NSP8,nsp8,Non-structural protein 8

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Quick Database Links

Gene Symbol

NSP8

UniProt

YP_009725304.1

UniProt Details

−

No UniProt data available

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols