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Silibinin

SKU: orb1307850

Description

Silibinin

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Images & Validation

Key Properties

CAS Number22888-70-6
MW482.44
Purity99.76% (May vary between batches)
FormulaC25H22O10
SMILESC(O)[C@@H]1[C@H](OC=2C(O1)=CC=C(C2)[C@H]3OC=4C(C(=O)[C@@H]3O)=C(O)C=C(O)C4)C5=CC(OC)=C(O)C=C5
TargetAutophagy|||Reactive Oxygen Species
SolubilityEthanol:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (6.84 mM);DMSO:260 mg/mL (538.93 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

In Vivo
Research indicates that silibinin protects liver cells from toxin-induced damage, serving a hepatoprotective function. In vitro, studies demonstrate that silibinin exhibits anticancer effects against a variety of human cancer cells, including prostate cancer cells, estrogen-dependent/independent breast cancer cells, colorectal cancer cells, cervical cancer cells, and both small and non-small cell lung cancer cells. Silibinin is a mixture of the diastereoisomers silibinin A and silibinin B, approximately in a 1:1 ratio.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, inhibit, Autophagy, Reactive Oxygen Species, ReactiveOxygenSpecies, Silibinin A, Silibinin, Silybin, Silymarin I

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Protocol Information

Available Sizes

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100 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 90.00
DispatchUsually dispatched within 5-10 working days
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