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STAT5-IN-1

SKU: orb1225431

Description

A selective, small molecule inhibitor of the transcription factor STAT5 with IC50 of 47±17 uM in FP assays; shows little to no inhibition for STAT1, STAT3 and Lck (<40% inhibition at 500 uM); selectively inhibits the function of the STAT5b domain and STAT5 DNA binding in vitro, and selectively inhibits activation of STAT5 in K562 cells.

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Key Properties

CAS Number285986-31-4
MW293.28
Purity>98% (HPLC)
FormulaC16H11N3O3
SMILESO=C(N/N=C/C1=COC2=C(C=CC=C2)C1=O)C3=CN=CC=C3
TargetSTAT
SolubilityDMSO: ≥23.0 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Signal Transducers and Activators of Transcription 5

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STAT5-IN-1 (orb1225431)

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200 mg
500 mg
5 mg
$ 90.00
10 mg
$ 140.00
25 mg
$ 270.00
50 mg
$ 440.00
100 mg
$ 730.00