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SU3327

SKU: orb1218065

Description

SU3327 is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).

Images & Validation

Key Properties

CAS Number40045-50-9
MW261.3
Purity>98% (HPLC)
FormulaC5H3N5O2S3
SMILESNc1nnc(Sc2ncc([N+]([O-])=O)s2)s1
TargetJNK
SolubilityDMSO:62.5 mg/mL (239.19 mM; Need ultrasonic)

Bioactivity

In Vivo
Animal model: Male BKS. Cg-+Leprdb/+Leprdb/OlaHsd db/db mice (11-week-old) injected with insulin. Dosage: 25 mg/kg. Administration: Intraperitoneal injection. Result: Resulted in a statistically significant reduction in blood glucose levels.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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    40045-50-9

    261.3

    C5H3N5O2S3

    2 mg, 25 mg, 50 mg, 100 mg, 5 mg, 10 mg, 1 ml x 10 mM (in DMSO)
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SU3327 (orb1218065)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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Available Sizes

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200 mg
500 mg
2 mg
$ 70.00
5 mg
$ 110.00
10 mg
$ 160.00
25 mg
$ 270.00
50 mg
$ 450.00
100 mg
$ 670.00