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SuperKillerTRAIL, Soluble Recombinant Protein
SKU: orb1230075
Description
Images & Validation
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| Application Notes |
|---|
Key Properties
−| Source | E. coli |
|---|---|
| Biological Activity | Induces apoptosis at concentrations of >10ng/ml as tested on human tumor cells. This effect can be efficiently blocked by recombinant mouse TRAIL receptors. This protein does not require a cross-linker (enhancer) for its potent biological activity. |
| Target | Tnfsf10 |
| Tag | His Tag |
| Protein Sequence | The extracellular domain of mouse TRAIL (aa 99-291) is fused at the N-terminus to a His-tag and a linker peptide. The active multimeric conformation is stabilized by an inserted mutation allowing an additional CC-bridge. |
| Purity | >95% (SDS-PAGE). Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza). |
Storage & Handling
−| Storage | Once thawed it is recommended to prepare appropriate aliquots and to store them at -80°C. |
|---|---|
| Form/Appearance | Liquid |
| Buffer/Preservatives | In 20mM HEPES, pH 7.4, 300mM NaCl, 0.01% Tween 20, 1% sucrose, 1mM DTT. |
| Concentration | 0.5 mg/ml |
| Dry Ice Shipping | Please note: This product requires shipment on dry ice. A dry ice surcharge will apply. |
| Disclaimer | For research use only |
Alternative Names
−TRAIL, Apo-2L, TNFSF10, CD253
Similar Products
−SuperKillerTRAIL, Soluble Recombinant Protein [orb1230076]
>98% (SDS-PAGE). Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
E. coli
20 μg
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SuperKillerTRAIL, Soluble Recombinant Protein (orb1230075)
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