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TLR7/8 agonist 9

SKU: orb1944361

Description

TLR7/8 agonist 9 (Compound 25a), with EC50 values of 40 nM for hTLR7 and 23 nM for hTLR8, demonstrates anti-tumor properties and enhances the efficacy of PD-1/PD-L1 blockade treatments, making it valuable for cancer immunotherapy research.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number2649170-17-0
MW366.46
FormulaC20H26N6O
SMILESN(CCOC)C=1C2=C(C=CC(CC3=CC=C(CN(C)C)C=C3)=N2)N=C(N)N1
TargetOthers,TLR

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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TLR7/8 agonist 9 (orb1944361)

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