(±)-10-Hydroxycamptothecin

SKU: orb1308344

Description

(±)-10-Hydroxycamptothecin is a natural alkaloid derived from Camptotheca acuminata that acts as a selective inhibitor of DNA topoisomerase I. It serves as a key research compound for studying anticancer mechanisms and has been used in both in vitro cytotoxicity assays and in vivo tumor model studies to evaluate its therapeutic potential.

Research Area

Molecular Biology

Images & Validation

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Key Properties

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CAS Number	64439-81-2
MW	364.35
Purity	99.58% (May vary between batches)
Formula	C₂₀H₁₆N₂O₅
SMILES	CCC1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)cc4cc3Cn1c2=O
Target	Topoisomerase
Solubility	DMSO:29.71 mg/mL (81.54 mM)

Storage & Handling

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Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Topoisomerase, Topo I, Inhibitor, Hydroxy Camptothecine, inhibit, (±) 10 Hydroxycamptothecin, (±)10Hydroxycamptothecin, 10-Hydroxycamptothecin

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Compound Identifiers

PubChem CID

4330531 ↗

Key Properties

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No computed properties available.

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