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Butin

SKU: orb1710189

Description

Butin

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number21913-99-5
MW272.25
Purity99.91%
FormulaC15H12O5
SMILESO=C1C2=CC=C(O)C=C2OC(C3=CC=C(O)C(O)=C3)C1
TargetAntioxidant
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (12.12 mM);DMSO:80 mg/mL (293.85 mM)

Bioactivity

In Vivo
Butin significantly alleviates myocardial infarction and improves heart function, together with prevents diabetes-induced cardiac oxidative damage in rats .
In Vitro
Methods: H9c2 cells were treated with Butin (12.5, 25, 50 μM, 6 hours). Cell viability was detected by MTT assay, target protein expression was detected by Western blotting, and target gene expression was detected by real-time qPCR. Results: Butin increased cell survival in a dose-dependent manner, increased the expression of GSH-px, GSH, SOD, CAT, and HO-1, and increased the level of Nrf2 in the cytoplasm and nucleus in a dose-dependent manner, and enhanced the expression of GSH-px, GSH, SOD, CAT, and HO-1.

Storage & Handling

Storagekeep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Butin

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Key Properties

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Butin (orb1710189)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 mg
$ 120.00
5 mg
$ 190.00
1 ml x 10 mM (in DMSO)
$ 230.00
10 mg
$ 240.00
25 mg
$ 400.00
50 mg
$ 1,040.00
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